SYNTHESES VIA VINYL SULFONES .71. APPLICATION OF THE GRUBBS RING-CLOSING METATHESIS FOR THE CONSTRUCTION OF A MACROCYCLIC ANSA-BRIDGE - SYNTHESIS OF THE TRICYCLIC CORE OF ROSEOPHILIN

Authors
KIM SH FIGUEROA I FUCHS PL
Citation
Sh. Kim et al., SYNTHESES VIA VINYL SULFONES .71. APPLICATION OF THE GRUBBS RING-CLOSING METATHESIS FOR THE CONSTRUCTION OF A MACROCYCLIC ANSA-BRIDGE - SYNTHESIS OF THE TRICYCLIC CORE OF ROSEOPHILIN, Tetrahedron letters, 38(15), 1997, pp. 2601-2604
Citations number
30
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
15
Year of publication
1997
Pages
2601 - 2604
Database
ISI
SICI code
0040-4039(1997)38:15<2601:SVVS.A>2.0.ZU;2-U
Abstract
Metalation/alkylation of the pyrrole-fused 10 pi anion 15 regiospecifi cally yields the beta-alkylated ketones 16,17, Conversion of 17 to die ne 24 followed by Grubbs ring-closing metathesis provides 29 which is transformed to the roseophilin tricyclic core structure 5. (C) 1997 El sevier Science Ltd.