BIOSYNTHESIS OF 20-HYDROXYECDYSONE IN AJUGA HAIRY ROOTS - HYDROGEN MIGRATION FROM C-6 TO C-5 DURING CIS-A B RING FORMATION/

Authors
FUJIMOTO Y KUSHIRO T NAKAMURA K
Citation
Y. Fujimoto et al., BIOSYNTHESIS OF 20-HYDROXYECDYSONE IN AJUGA HAIRY ROOTS - HYDROGEN MIGRATION FROM C-6 TO C-5 DURING CIS-A B RING FORMATION/, Tetrahedron letters, 38(15), 1997, pp. 2697-2700
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
15
Year of publication
1997
Pages
2697 - 2700
Database
ISI
SICI code
0040-4039(1997)38:15<2697:BO2IAH>2.0.ZU;2-P
Abstract
Feeding of deuterium labeled cholesterols including [6-H-2]cholesterol and [3 alpha,6-H-2(2)]cholesterol to hairy roots of Ajuga reptans var . atropurpurea followed by H-2-NMR analysis of the biosynthesized 20-h ydroxyecdysone revealed that most of the deuterium atom located at C-6 of cholesterol migrated to the C-5 position of 20-hydroxyecdysone. (C ) 1997 Elsevier Science Ltd.