The thalamus is a nuclear complex situated in the diencephalon. Besides a n
euro-anatomical description of the thalamus, this article reviews the curre
nt knowledge on the functional anatomy of the three functional classes of t
halamic nuclei : specific, non-specific and association nuclei. As the majo
rity of the pathology affecting the thalamus is of cerebrovascular origin,
the vascularisation of the human thalamus will be reviewed as well. Finally
, the knowledge of the functional anatomy and the vascularisation of`the hu
man thalamus will be integrated in the review of the semeiology, of thalami
c syndromes. Besides its function as a relay centre in subserving sensory a
nd motor mechanisms, the thalamus participates in various neurocognitive pr
ocesses such as memory and language. The current knowledge on these topics
will be reviewed as well.