J. Saez et al., In vitro array type standard for the evaluation of insecticide activity inPiper auritum leaves (Piperaceae)., AFINIDAD, 55(477), 1998, pp. 363-368
On this work we present a study based on a matrix statistical model to eval
uate the insecticidal activity of different polarity extracts of Piper auri
tum leaves on the biological model: Drosophila melanogaster. The division o
f the dichloromethane extract which showed more activity, allowed the isola
tion and identification of safrole as the responsible compound of the activ
ity. The matrix statistical model used is useful to determine the percentag
es of mortality as a dependence of the concentration and the time, opposed
with the traditional models which the time is considered as a constant when
the dosis with activity are determined.