Effects of tea infusions of various varieties or different manufacturing types on inhibition of mouse mast cell activation

We investigated effects of various tea infusions on mast cell activation us ing mouse mast cells. Among various tea extracts, infusions from cultivar ' Benihomare' and Taiwan lineage strongly inhibited histamine release after F c epsilon RI cross-linking. Among three types of tea (from cultivar 'Beniho mare'), extract from oolong tea or black tea inhibited histamine release mo re strongly than green tea extract. Furthermore, 'Benihomare' oolong tea ex tract suppressed tyrosine phosphorylation of cellular proteins after Fc eps ilon RI cross-linking, but polyvinyl polypyrrolidone treatment of the extra ct to remove phenolic compounds, weakened the suppressive effect.