Elevated plasma levels of homocysteine in Parkinson's disease

Authors
Kuhn, W Roebroek, R Blom, H van Oppenraaij, D Przuntek, H Kretschmer, A Buttner, T Woitalla, D Muller, T
Citation
W. Kuhn et al., Elevated plasma levels of homocysteine in Parkinson's disease, EUR NEUROL, 40(4), 1998, pp. 225-227
Citations number
10
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
EUROPEAN NEUROLOGY
ISSN journal
00143022 → ACNP
Volume
40
Issue
4
Year of publication
1998
Pages
225 - 227
Database
ISI
SICI code
0014-3022(1998)40:4<225:EPLOHI>2.0.ZU;2-P
Abstract
Significantly elevated plasma levels of homocysteine, but not cysteine and cysteinylglycine, were found in treated parkinsonian patients compared to c ontrols. Elevated levels of homocysteine may be either caused by an unknown endogenous metabolic disturbance or by antiparkinsonian treatment, because no association to severity or duration of disease was found. Based on the results of this study one may speculate that homocysteine may be an indepen dent risk factor for vascular disease in Parkinson's disease.