Massive intracranial immature teratoma with extracranial extension into oral cavity, nose, and neck

We present a case of congenital massive intracranial teratoma with extracra nial extension into oral cavity, nose, and neck diagnosed by antenatal ultr asonography at 25 weeks of gestation. The fetus was delivered by cesarean s ection because of massive fetal head size and severe maternal pregnancy-ind uced hypertension. At necropsy the tumor was found to be an immature terato ma, with no recognizable normal brain tissue. An additional finding was hep atomegaly secondary to extensive extramedullary hematopoiesis. Karyotyping of both the fetus and the teratoma revealed a normal female chromosomal com position: 46,XX.