DNA short tandem repeat profiling of Chinese population in Taiwan determined by using an automated sequencer

We performed a population study on a Taiwan population using a set of nine short tandem repeat (STR) loci and the amelogenin locus. Allele and genotyp e frequencies of the STR systems D3S1358, vWA, FGA, TH01, TPOX, CSF1PO, D5S 818, D13S317 and D7S820 were determined by polymerase chain reaction follow ed by automated sequencer analysis. A total of 80 alleles could be observed , using all systems, in a population of 500 individuals. No new intermediat e fragments were found in these systems. Allele frequencies showed no devia tion from the Hardy-Weinberg equilibrium. The mean exclusion power (MEP) ra nged from 0.294 for TPOX to 0.711 for FGA (the combined MEP was >0.999), th e discriminating power (DP) ranged from 0.782 for TPOX to 0.964 for FGA, (t he combined DP was >0.99999999949). (C) 1998 Elsevier Science Ireland Ltd A ll rights reserved.