Acid secretion from an esophageal inlet patch demonstrated by ambulatory pH monitoring

Heterotopic gastric mucosa may occur throughout the gastrointestinal tract, including the upper esophagus. The capability of this ectopic mucosa to se crete acid has been suggested in different reports. We report for the first time a case of heterotopic gastric mucosa in the upper esophagus complicat ed by a stricture with secretion of acid demonstrated by prolonged ambulato ry pH monitoring. Lansoprazole, 30 mg twice daily, produced symptom resolut ion, and repeat ambulatory pH showed complete acid suppression in the proxi mal esophagus.