Artificial insemination by husband in unexplained infertility compared with infertility associated with peritoneal endometriosis

There have been numerous inconclusive studies examining the differences bet ween unexplained and peritoneal endometriosis-associated infertility. Hence , the choice of artificial reproductive technique may be difficult. This pr ospective study compares outcome in couples with unexplained infertility an d with minimal or mild endometriosis-associated infertility, undergoing tre atment with ovarian stimulation combined with artificial insemination by hu sband. No differences were found between the unexplained infertile and the endometriosis group as to patient characteristics, response to ovarian stim ulation and semen qualities. There was a significantly higher total pregnan cy rate,,vith more multiple gestations, in the unexplained infertile compar ed with the endometriosis group. The difference in outcome could reflect di fferences in pathogenesis and aetiology for the two groups.