Objective: The study was designed 1) to examine the prevalence of depressio
n in patients with congestive heart failure (CHF); 2) to explore associatio
ns between the physician's rating of functional status (NYHA class) and pat
ient's assessment of functional status (physical limitation, dyspnea) with
symptoms of depression; and 3) to explore gender related differences in rel
ation to physician's rating and patient's rating of function status, and sy
mptoms of depression. Method: A sample of 119 clinically stable heart failu
re patients (85 males and 34 females) was recruited from an outpatient card
iology hospital practice. The patients underwent a physical examination and
completed a set of questionnaires. Prevalence of depressive symptoms and t
he association of these symptoms with NYHA class and patient's perceived fu
nctional status was studied. Results: Findings indicate that depressive sym
ptoms were not predominant among this sample of CHF patients. Path analyses
showed non-significant direct associations between NYHA class as well as p
atient's perception of dyspnea with depression. In contract, the subjective
indicator of physical limitations was strongly associated with symptoms of
depression among the males, but this relation was not significant among th
e females. Conclusions: Results suggest that men and women respond differen
tly to the burden of heart failure. However, interpretation of the results
from the present study should be considered as tentative and additional res
earch is required to examine mechanisms that explain gender differences in
response to heart failure.