114,005 cases from 40 United States series of laparoscopic cholecystectomie
s (LC) were reviewed. Indications, conversion rates, rates of intra-operati
ve cholangiography (IOC), and incidence of bile duct stone and iatrogenic b
ile duct injuries were assessed. Indications included acute cholecystitis i
n 11.6% and gallstone pancreatitis in 2.1% of reported cases. Conversion ra
te was to be primarily related to inflammation. Unsuspected bile duct stone
s were detected intra-operatively in 7.8% of cases. 561 major bile duct inj
uries (BDI) and 401 bile leaks (BL) were recorded and acute or chronic infl
ammation was their most important potential predisposing factor, In series
with a high rate of IOC performed during LC, BDJ and BL were slightly lower
and lesions recognized intra-operatively were much higher than in series w
ith low rate of IOC. BDJ occurred in the first 50 patients of the surgeon's
experience in about 91% of the cases.