Iron deficiency anemia due to a Brunner's gland hamartoma

Brunner's gland hamartomas are rare benign duodenal tumors often discovered incidentally during endoscopy or on an upper gastrointestinal series. Thes e tumors arise mainly in the duodenal bulb and can present with gastrointes tinal bleeding or symptoms of intestinal obstruction. When symptomatic, sur gical or endoscopic removal can be safely performed and the prognosis is ve ry good. We describe a 63-year-old man presenting with iron deficiency anem ia due to a large Brunner's gland hamartoma and review the endoscopic, radi ologic, surgical, and pathologic findings.