A HhaI/BstUI polymorphism in a novel gene at human chromosome 11p15.5

Authors
Miura, K Masuzaki, H Ishimaru, T Niikawa, N Jinno, Y
Citation
K. Miura et al., A HhaI/BstUI polymorphism in a novel gene at human chromosome 11p15.5, J HUM GENET, 43(4), 1998, pp. 283-284
Citations number
6
Categorie Soggetti
Molecular Biology & Genetics
Journal title
JOURNAL OF HUMAN GENETICS
ISSN journal
14345161 → ACNP
Volume
43
Issue
4
Year of publication
1998
Pages
283 - 284
Database
ISI
SICI code
1434-5161(1998)43:4<283:AHPIAN>2.0.ZU;2-7
Abstract
We found a HhaI/BstUI polymorphism in the 3' untranslated region of a novel gene which was localized to 11p15.5. This region is one of prominent impri nting domains and contains multiple imprinted genes, such as H19, IGF2, KVL QT1, and p57(KIP2), Which suggests that regional factors might contribute t o the imprinting. This polymorphism will be useful in the allelic analysis of expression and methylation of the novel gene.