Simple methods for the labelling of N-methyl amines using isotopically labelled methyl iodide.

Authors
Fellows, I Carr, RM deBoeck, N Montgomery, S Waterhouse, L Sutherland, DR
Citation
I. Fellows et al., Simple methods for the labelling of N-methyl amines using isotopically labelled methyl iodide., J LABEL C R, 41(12), 1998, pp. 1127-1143
Citations number
11
Categorie Soggetti
Chemistry & Analysis","Inorganic & Nuclear Chemistry
Journal title
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
ISSN journal
03624803 → ACNP
Volume
41
Issue
12
Year of publication
1998
Pages
1127 - 1143
Database
ISI
SICI code
0362-4803(199812)41:12<1127:SMFTLO>2.0.ZU;2-W
Abstract
Methods for the synthesis of isotopically labelled N-methyl amines using th e target amine and isotopically labelled methyl iodide in a quaternisation/ dequaternisation strategy are described. The method has been further refine d to allow the synthesis of such amines without any isotopic dilution.