FOCAL NODULAR HYPERPLASIA OF THE LIVER - SERIAL MRI WITH GD-DOTA, SUPERPARAMAGNETIC IRON-OXIDE, AND GD-EOB-DTPA

Background: To demonstrate the improved specificity of liver MRI in di agnosis of focal nodular hyperplasia (FNH) using liver specific contra st agents. Methods: In a patient after resected adenosarcoma of the ut erus a focal nodular hyperplasia was followed. Serial MRI of the liver was performed using first Gd-DOTA, followed by superparamagnetic iron oxide (SPIO) as well as Gd-EBB-DTPA. Results: During the follow-up of FNH specificity of liver MRI improved using liver specific contrast a gents. The central scar as well as the pseudocapsule showed different typical contrast uptake using all three methods. Conclusion: Serial MR I of the liver with Gd-DOTA, SPIO and Gd-EOB-DTPA can exclude a malign ant liver lesion, Liver biopsy of FNH can be avoided with increased sp ecificity of MRI for FNH.