Labeling of ornidazole with iodine-131

Authors
Asikoglu, M Yurt, F Unak, P
Citation
M. Asikoglu et al., Labeling of ornidazole with iodine-131, J RAD NUCL, 237(1-2), 1998, pp. 143-145
Citations number
10
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
ISSN journal
02365731 → ACNP
Volume
237
Issue
1-2
Year of publication
1998
Pages
143 - 145
Database
ISI
SICI code
0236-5731(199811)237:1-2<143:LOOWI>2.0.ZU;2-6
Abstract
Ornidazole (1-(3-chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole) was lab eled with iodine-131 by using iodogen method. Quality controls were perform ed by instant thin layer chromatography (ITLC) and electrophoresis methods. Labeling yield was 91%. Iodination was carried out by substitution of chlo ride by iodine-131. Structure was confirmed by H-1-NMR.