Systemic candidosis and concomitant aspergillosis and zygomycosis in two Amazon parakeets (Amazona aestiva)

Systemic candidosis and concomitant aspergillosis and zygomycosis were diag nosed immunohistochemically in two Amazon parakeets (Amazona aestiva). In t he bird with systemic candidosis, subacute necrotic lesions were present in the lung and the gastrointestinal tract, whereas chronic giant cell-contai ning granulomas were located in the liver, heart, spleen and on the serosal lining of the small intestine. Although the lesions in the liver, heart an d spleen most likely developed as a result of haematogenous spread, the gra nulomas on the serosal surface may have developed after a local transmural intestinal invasion. In the second bird, aspergillosis and zygomycosis were restricted to the lung, whereas some zygomycetes were found in the air sac s as well as in the heart and kidneys. In all organs the zygomycotic lesion s were dominated by thrombosing vasculitis, supporting haematogenous dissem ination.