Sclerosing sweat-duct carcinoma (malignant syringoma) of the upper eyelid:A patient report with immunohistochemical and ultrastructural analysis

Sclerosing sweat-duct carcinoma or malignant syringoma is a rare eyelid tum or. The authors report the first patient with sclerosing sweat-duct carcino ma involving the upper eyelid and present its immunohistochemical and ultra structural features. The clinical features and the histopathologic and ultr astructural findings that distinguish this tumor from its benign counterpar ts are discussed. Sclerosing sweat-duct carcinomas are slow growing but loc ally invasive neoplasms that have a propensity to recur. Wide and deep surg ical excision with frozen section evaluation of margins is recommended.