Objective. To investigate "up-to-date" and "age-appropriate" indicators of
preschool vaccination status and their implications for vaccination policy.
Methods. The authors analyzed medical records data from the Baltimore Immun
ization Study for 525 2-year-olds born from August 1988 through March 1989
to mothers living in low-income Census tracts of the city of Baltimore.
Results. While only 54% of 24-month-old children were up-to-date for the pr
imary series. indicators of up-to-date coverage were consistently higher, b
y 37 or more percentage points, than corresponding age-appropriate indicato
rs. Almost 80% of children who failed to receive the first dose of DTP or O
PV age-appropriately failed to be up-to-date by 24 months of age for the pr
imary series.
Conclusions, Age-appropriate immunization indicators more accurately reflec
t adequacy of protection for preschoolers than up-to-date indicators at bot
h the individual and population levels. Age-appropriate receipt of the firs
t dose of DTP should be monitored to identify children likely to be underim
munized. Age-appropriate indicators should also be incorporated as Vaccinat
ion coverage estimators in population-based surveys and as quality of care
indicators for managed care organizations, These changes would require accu
rate dates for each Vaccination and support the need to develop population-
based registries.