A comparative study of C-2-symmetric bis(aziridine) ligands in some transition metal-mediated asymmetric transformations

Authors
Tanner, D Johansson, F Harden, A Andersson, PG
Citation
D. Tanner et al., A comparative study of C-2-symmetric bis(aziridine) ligands in some transition metal-mediated asymmetric transformations, TETRAHEDRON, 54(51), 1998, pp. 15731-15738
Citations number
24
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
54
Issue
51
Year of publication
1998
Pages
15731 - 15738
Database
ISI
SICI code
0040-4020(199812)54:51<15731:ACSOCB>2.0.ZU;2-Y
Abstract
A comparative study has been made of the performance of differently substit uted Ca-symmetric bis(aziridine) ligands in a variety of metal-mediated asy mmetric reactions. The metals studied were osmium (dihydroxylation), pallad ium (allylic alkylation) and copper (cyclopropanation and aziridination), t he ligands being chosen so as to allow evaluation of both electronic and st eric effects. The electronic effects were most pronounced for complexes of palladium, which seem to bind rather loosely to this type of ligand. For th e other metals, steric effects play a more important role. (C) 1998 Elsevie r Science Ltd. All rights reserved.