The search for the perfect surgical ''glue'' is ongoing. Throughout the cen
turies, surgeons and scientists have sought an ideal sealant and adhesive:
one that is safe, biologically compatible, effective, and affordable. A tis
sue sealant with these attributes would have unlimited applications in the
field of plastic and reconstructive surgery. Simple wound closure, sealing
of cavities, attachment of graft and flaps, and decreasing of bleeding, bru
ising, and edema are problems that ail aesthetic and reconstructive surgeon
s face every day in their practice.