Transfer of streptomycin biosynthesis gene clusters within streptomycetes isolated from soil

Authors
Egan, S Wiener, P Kallifidas, D Wellington, EMH
Citation
S. Egan et al., Transfer of streptomycin biosynthesis gene clusters within streptomycetes isolated from soil, APPL ENVIR, 64(12), 1998, pp. 5061-5063
Citations number
20
Categorie Soggetti
Biology,Microbiology
Journal title
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
ISSN journal
00992240 → ACNP
Volume
64
Issue
12
Year of publication
1998
Pages
5061 - 5063
Database
ISI
SICI code
0099-2240(199812)64:12<5061:TOSBGC>2.0.ZU;2-W
Abstract
Streptomyces strains isolated from soil were found to possess various numbe rs of genes from the streptomycin biosynthesis cluster. The strains missing genes from the cluster also lacked the ability to produce streptomycin. Tw o of the isolates which contain only part of the cluster are apparently rec ipients of a gene transfer event. The implications for the role of gene tra nsfer in antibiotic evolution are discussed.