Synthesis of praziquantel derivatives and their in vitro activity against adult Clonorchis sinensis

Authors
Kim, CS Min, DY
Citation
Cs. Kim et Dy. Min, Synthesis of praziquantel derivatives and their in vitro activity against adult Clonorchis sinensis, ARCH PH RES, 21(6), 1998, pp. 744-748
Citations number
10
Categorie Soggetti
Pharmacology & Toxicology
Journal title
ARCHIVES OF PHARMACAL RESEARCH
ISSN journal
02536269 → ACNP
Volume
21
Issue
6
Year of publication
1998
Pages
744 - 748
Database
ISI
SICI code
0253-6269(199812)21:6<744:SOPDAT>2.0.ZU;2-3
Abstract
Several praziquantel derivatives have been prepared by the acylation of com pound 5, and examined on their biological activity in vitro against adult C lonorchis sinensis collected from rabbits infected with metacercariae which was isolated from Pseudorasbora parva, a second intermediate host, capture d in Nakdong river in Korea.