Cs. Kim et Dy. Min, Synthesis of praziquantel derivatives and their in vitro activity against adult Clonorchis sinensis, ARCH PH RES, 21(6), 1998, pp. 744-748
Several praziquantel derivatives have been prepared by the acylation of com
pound 5, and examined on their biological activity in vitro against adult C
lonorchis sinensis collected from rabbits infected with metacercariae which
was isolated from Pseudorasbora parva, a second intermediate host, capture
d in Nakdong river in Korea.