PROTEINURIA AND ALBUMIN HOMEOSTASIS IN THE NEPHROTIC SYNDROME - EFFECT OF DIETARY-PROTEIN INTAKE

Nephrotic syndrome is analyzed in the light of interventions designed to decrease proteinuria and renal injury. The effect of dietary protei n intake on urinary protein losses and albumin homeostasis are discuss ed on the basis of the pathophysiologic mechanisms known to account fo r changes in renal function of nephrotic patients. In addition, the ef fect of angiotensin-converting enzyme inhibitors for reduction of prot einuria is discussed in terms of the modulation of glomerular permsele ctivity and hemodynamics.