Thrombopoietin concentration in umbilical cord blood of healthy term newborns is higher than in adult controls

Authors
Walka, MM Sonntag, J Dudenhausen, JW Obladen, M
Citation
Mm. Walka et al., Thrombopoietin concentration in umbilical cord blood of healthy term newborns is higher than in adult controls, BIOL NEONAT, 75(1), 1999, pp. 54-58
Citations number
21
Categorie Soggetti
Medical Research General Topics
Journal title
BIOLOGY OF THE NEONATE
ISSN journal
00063126 → ACNP
Volume
75
Issue
1
Year of publication
1999
Pages
54 - 58
Database
ISI
SICI code
0006-3126(199901)75:1<54:TCIUCB>2.0.ZU;2-G
Abstract
Thrombopoietin (TPO) concentrations were determined in umbilical cord plasm a of 121 healthy term newborns, The lower detection limit of the enzyme imm unoassay employed was 32.5 pg/ml. Median cord plasma TPO concentration was 78 (interquartile range 55-107) pg/ml, 95th percentile was 255 pg/ml, In on ly 8% (10/121), TPO was below the detection limit compared to 81% of health y adults (25/31). In cord blood and adult controls, there were no significa nt correlations of TPO with platelet count or mass.