Bone marrow transplantation as treatment for X-linked immunodeficiency with hyper-IgM

Authors
Bordigoni, P Auburtin, B Carret, AS Schuhmacher, A Humbert, JC Le Deist, F Sommelet, D
Citation
P. Bordigoni et al., Bone marrow transplantation as treatment for X-linked immunodeficiency with hyper-IgM, BONE MAR TR, 22(11), 1998, pp. 1111-1114
Citations number
12
Categorie Soggetti
Hematology,"Medical Research Diagnosis & Treatment
Journal title
BONE MARROW TRANSPLANTATION
ISSN journal
02683369 → ACNP
Volume
22
Issue
11
Year of publication
1998
Pages
1111 - 1114
Database
ISI
SICI code
0268-3369(199812)22:11<1111:BMTATF>2.0.ZU;2-N
Abstract
We report a 10-year-old boy with a severe form of immunodeficiency with hyp er-IgM who underwent successful bone marrow transplantation with his HLA-ma tched sister as donor. Busulfan (20 mg/kg) and cyclophosphamide (200 mg/kg) were used as conditioning. The post-transplant course was uneventful. He i s alive 25 months later with full hematological and immunological reconstit ution.