We describe an unusual case of a late presentation of a fungal brain absces
s in a non-neutropenic child 1 year after completing chemotherapy for M5 ac
ute myeloid leukaemia (AML). Biopsy of the mass identified candidal hyphae
and the patient was treated with 5 mg/kg of liposomal amphotericin B for 6
weeks. The lesion resolved completely and the child remains well 2 years la
ter. Invasive fungal infection should be included in the differential diagn
osis of unexplained symptoms in patients who have previously received inten
sive chemotherapy.