Leeches are commonly used in the postoperative course of plastic surgical o
perations where there is venous congestion in a pedicled or free flap. They
provide a temporary relief to venous engorgement whilst venous drainage is
re-established. It is known that leeches can carry Aeromonas hydrophila in
fection, and a second or third generation cephalosporin antibiotic has trad
itionally been given as prophylaxis against infection. We report a new obse
rvation that leeches can carry Serratia marcescens and give rise to clinica
lly significant infection. The implication for prophylaxis and treatment of
leech-associated cellulitis is discussed.