Micellar electrokinetic chromatography

A review of the research on micellar electrokinetic chromatography (MEKC), carried out mainly in our laboratory, is described from the viewpoints of ( 1) fundamental characteristics of MEKC, such as the separation principle, c hromatographic parameters, selectivity and resolution, thermodynamic parame ters, retention index, and band broadening; (2) selectivity manipulation, i ncluding effects of surfactants, temperature, pH, and various additives; (3 ) on-line coupling of MEKC with mass spectrometry; (4) applications, such a s the separation of closely related compounds and enantiomer separations; a nd (5) on-line neutral sample concentration techniques.