Synthesis of carbosilane compounds functionalized with three or four beta-cyclodextrin moieties. Use of a one-pot reaction in liquid ammonia for birch reduction and the subsequent S(N)2 replacement

As a basic model reaction for assembling specific functional carbohydrate m olecules on a novel core substance by making covalent bonds, an efficient o ne-pot reaction involving Birch reduction and a subsequent S-N(2) replaceme nt was developed, employing trivalent and tetravalent carbosilane bromides as the core and monodeoxy-monomercapto-beta-cyclodextrin as the functional carbohydrate. It was confirmed that carbosilane derivatives containing a su itable spacer molecule were of wide applicability as a new core substance f or the construction of diverse functional materials.