A new cinchona-modified platinum catalyst for the enantioselective hydrogenation of pyruvate: the structure of the 1 : 1 alkaloid-reactant complex

Authors
Bartok, M Felfoldi, K Torok, B Bartok, T
Citation
M. Bartok et al., A new cinchona-modified platinum catalyst for the enantioselective hydrogenation of pyruvate: the structure of the 1 : 1 alkaloid-reactant complex, CHEM COMMUN, (23), 1998, pp. 2605-2606
Citations number
24
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
23
Year of publication
1998
Pages
2605 - 2606
Database
ISI
SICI code
1359-7345(199812):23<2605:ANCPCF>2.0.ZU;2-V
Abstract
The hydrogenation of ethyl pyruvate to (S)-ethyl lactate (up to 70% ee) ove r a Pt/Al2O3 catalyst using alpha-isocinchonine as a modifier strongly supp orts the structure of the intermediate complex [cinchona alkaloid (open con former)-pyruvate 1:1 complex] of this type of reactions.