Jlr. Arrondo et Fm. Goni, Infrared studies of protein-induced perturbation of lipids in lipoproteinsand membranes, CHEM PHYS L, 96(1-2), 1998, pp. 53-68
The paper reviews the main recent publications concerning infrared (IR) spe
ctroscopy as applied to the study of lipid-protein interactions in model an
d cell membranes, lipoproteins, and related systems (e.g. lung surfactant).
The review focuses mainly on transmission IR. Based on the available data,
a number of general conclusions are presented on the perturbations caused
by proteins on either the hydrocarbon chains, the polar headgroups or the i
nterface region. Lipid-protein interactions in native cell membranes do not
reveal significant differences from what is observed in semisynthetic mode
l systems. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.