Influence of feeding on metabolite excretion evidenced by urine H-1 NMR spectral profiles: a comparison between subjects living in Rome and subjects living at arctic latitudes (Svaldbard)

Urines from 25 normal subjects living in Rome and 25 normal subjects living in Ny-Alesund (Svaldbard) were analysed by (HNMR)-H-1 spectroscopy. The ob served differences in the concentration of the major metabolites were corre lated to the composition of the diet. It was found that a diet rich of carb ohydrates, such as the Italian diet, is responsible for an increased excret ion of citrate, lactate, alanine, and glycine. Thus, a correct diagnostical interpretation of urinary metabolites needs to consider feeding habits. (C ) 1998 published by Elsevier Science B.V. All rights reserved.