The role of gas chromatography mass spectrometry - Instrumental techniquesin forensic urine drug testing

Authors
Citation
M. Lehrer, The role of gas chromatography mass spectrometry - Instrumental techniquesin forensic urine drug testing, CLIN LAB M, 18(4), 1998, pp. 631
Citations number
18
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology
Journal title
CLINICS IN LABORATORY MEDICINE
ISSN journal
02722712 → ACNP
Volume
18
Issue
4
Year of publication
1998
Database
ISI
SICI code
0272-2712(199812)18:4<631:TROGCM>2.0.ZU;2-2
Abstract
This article discusses the application of GC/MS instrument techniques to ur ine drug testing. Remember that GC/MS is a technique combining gas liquid c hromatography (GLC) separation with mass spectrometric detection. This mean s that good GC/MS results are highly dependent on good chromatographic para meters. Although it may seem self-evident, many users encounter GC.MS probl ems that could be readily avoided by optimizing chromatographic parameters. In fact, most GC/MS problems in the clinical or forensic toxicology labora tory are probably chromatographic in nature.