Buildings with indoor air quality (IAQ) complaints frequently have high air
borne concentrations of Penicillium species, while buildings with few IAQ c
omplaints have an indoor air (IDA) fungal ecology similar to outdoor air (O
DA), where Cladosporium species is usually the dominant microorganism. Thes
e studies compared fungal air profiles, measured continually over 6 h in a
documented sick building, in IDA in a room experiencing IAQ problems with f
ungal profiles measured concurrently in ODA. The dominant species collected
at both sites were Penicillium species, Cladosporium species, and Alternar
ia species. In the IDA, Penicillium species were always the dominant organi
sms, ranging from 150 to 567 cfu/m(3) (89.8-100% of the total fungi). In th
e ODA, Cladosporium species were dominant in four samples (40.0-70.6%), whi
le Penicillium species were dominant (52.7-79.6%) in two. These data demons
trate that, even though ODA fungal profiles are changing continuously, IDA
fungal profiles in "sick" buildings tend to remain unchanged.