The literature on cognitive function and Alzheimer's disease in non-insulin
-dependent diabetes, impaired glucose tolerance and hyperinsulinaemia are b
riefly summarized. Neuropsychological, epidemilogical and endocrine contrib
utions are reviewed, with an emphasis on the insulin hypothesis as a potent
ial pathophysiological mechanism for Alzheimer's disease. Curr Opin Neurol
11:673-677. (C) 1998 Lippincott Williams & Wilkins.