Male reproductive function has recently attracted increasing attention due
to reports on time-related decline in semen quality. Analysis of retrospect
ive data indicates that sperm counts may have declined in some parts of the
world, but there seem to be regional differences both in the quality of se
men and regarding the secular trend. Whereas data on sperm counts may be so
mewhat difficult to interpret, there is no doubt that incidence of testicul
ar cancer has increased worldwide. In occupational studies, only a few type
s of exposures were shown to have an impact on male reproductive function;
lifestyle and general environmental factors may play a more important role.
Prospective studies on secular and geographic trends in male reproductive
function are warranted.