1,2,4,5-tetrazine: Synthesis and reactivity in [4+2]cycloadditions

Authors
Sauer, J Heldmann, DK Hetzenegger, J Krauthan, J Sichert, H Schuster, J
Citation
J. Sauer et al., 1,2,4,5-tetrazine: Synthesis and reactivity in [4+2]cycloadditions, EUR J ORG C, (12), 1998, pp. 2885-2896
Citations number
77
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
1434193X → ACNP
Issue
12
Year of publication
1998
Pages
2885 - 2896
Database
ISI
SICI code
1434-193X(199812):12<2885:1SARI[>2.0.ZU;2-2
Abstract
Full details on the reactivity of the title compound as 4 pi component in i nverse-type Diels-Alder reactions, including kinetic data, are reported. Do nor-substituted alkynes, alkenes, donor-substituted and unsubstituted cyclo alkenes, ketene acetals and aminals, as well as several cyclic enol ethers were used as dienophiles in these investigations. A. number of 4-mono- and 4,5-disubstituted pyridazines can easily be obtained by this method.