This study investigated the psychological impact of HIV infection through a
ssessment of posttraumatic stress disorder in response to HIV infection. Si
xty-one HIV-positive homosexual/bisexual men were assessed for posttraumati
c stress disorder in response to HIV infection (PTSD-HIV) using a modified
PTSD module of the DIS-III-R. Thirty percent met criteria for a syndrome of
posttraumatic stress disorder in response to HIV diagnosis (PTSD-HIV). In
over one-third of the PTSD cases, the disorder had an onset greater than 6
months after initial HIV infection diagnosis. PTSD-HIV was associated with
other psychiatric diagnoses, particularly the development of first episodes
of major depression after HIV infection diagnosis. PTSD-HIV was significan
tly associated with a pre-HIV history of PTSD from other causes, and other
pre-HIV psychiatric disorders and neuroticism scores, indicating a similari
ty with findings in studies of PTSD from other causes. The findings from th
is preliminary study suggest that a PTSD response to HIV diagnosis has clin
ical validity and requires further investigation in this population and oth
er medically ill groups. The results support the inclusion of the diagnosis
of life-threatening illness as a traumatic incident that may lead to a pos
ttraumatic stress disorder, which is consistent with the DSM-IV criteria. (
C) 1998 Elsevier Science Inc.