Synthesis of pyrazolines and isoxazoles as potential antimicrobial agents.

m,m'-Bis-(p-acetophenylaminosulphonyl)-benzophenone 1 on condensation with various araldehydes yielded chalcones 2a-p which on cyclization with phenyl hydrazine and hydroxylamine hydrochloride furnished the corresponding m,m' -bis-(5-aryl-1-phenyl-pyrazolin-3-yl-p-phenylaminosulphonyl)-benzophenones 3a-p and m,m'-bis (5-arylisoxazol-3-yl-p-phenylaminosulphonyl)-benzophenone s 4a-p. The structure of the compounds have been confirmed from elemental a nalyses, IR, H-1 PMR and Mass spectral data, All the products have been eva luated for their in vitro growth inhibitory activity against different micr obes.