Outpatient parenteral anti-infective therapy for skin and soft-tissue infections

Skin and soft tissue infections (SSIs) are one of the many infectious disea ses that can be treated by outpatient parenteral antiinfective therapy (OPA T). Determining whether a patient with SSIs is treated topically, orally, o r parenterally depends on the severity of infection and host factors. The d ecision to hospitalize, initiate, or transition to OPAT with SSIs depends o n the medical assessment and consideration of available resources for OPAT. Anti-infective selection depends on the clinical presentation, likely orga nisms, pharmacodynamics, pharmacokinetics, and drug stability.