Objective: To compare symptoms and signs in women with single and mixed gen
ital infections. Methods: The study population comprised 996 apparently hea
lthy women. Gynecological symptoms and signs were looked for and diagnostic
s for the most prevalent gynecological infections were made. Results: When
co-infections were excluded, chlamydial infections, bacterial vaginosis and
cervical human papillomavirus infections were associated with a fishy malo
dor; for the two former conditions an easily bleeding ectopy was also found
. Vaginal candidosis showed characteristic symptoms and signs. Genital wart
s were associated with dysuria, general and lower abdominal pain. Out of 49
4 women with a genital infection, 112 (22.7%) had a mixed infection, which
in some cases influenced symptoms and signs. Conclusion: Many women who con
sider themselves gynecologically healthy, may nevertheless harbor one or mo
re infectious agents. The need to exclude multiple infections is obvious. P
ositive predictive values were for specific symptoms and signs were general
ly low. (C) 1998 International Federation of Gynecology and Obstetrics.