Chorea as a symptom of neuroborreliosis: a case study

Citation
I. Piccolo et al., Chorea as a symptom of neuroborreliosis: a case study, ITAL J NEUR, 19(4), 1998, pp. 235-239
Citations number
21
Categorie Soggetti
Neurology
Journal title
ITALIAN JOURNAL OF NEUROLOGICAL SCIENCES
ISSN journal
03920461 → ACNP
Volume
19
Issue
4
Year of publication
1998
Pages
235 - 239
Database
ISI
SICI code
0392-0461(199808)19:4<235:CAASON>2.0.ZU;2-5
Abstract
Borrelia burgdorferi (Bb) can cause a large number of neurological symptoms . Although extrapyramidal disturbances are rare (representing less than 2% of all neurological complications), diffuse choreic dyskinesias have been d escribed during the course of mild encephalitis. The data published in the literature suggest that there are clinical and neurological analogies betwe en neuroborreliosis and multiple sclerosis (MS). The presence of specific a nti-Bb antibodies in cerebrospinal fluid is a discriminating factor that al lows a diagnosis of neuroborreliosis to be made. We describe the case of a patient with Lyme disease, characterised by widespread chorea and behaviour al disturbances. Emphasis is placed on the atypical onset and evolution, th e difficulties encountered in formulating a diagnosis, and the uncertaintie s concerning the pathophysiology and clinical/neuroradiological correlation s of the disease.