Soluble CD27 in thyroid disorders

Authors
Kallio, P Murphy, ED
Citation
P. Kallio et Ed. Murphy, Soluble CD27 in thyroid disorders, J LA CL MED, 132(6), 1998, pp. 478-482
Citations number
32
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research General Topics
Journal title
JOURNAL OF LABORATORY AND CLINICAL MEDICINE
ISSN journal
00222143 → ACNP
Volume
132
Issue
6
Year of publication
1998
Pages
478 - 482
Database
ISI
SICI code
0022-2143(199812)132:6<478:SCITD>2.0.ZU;2-3
Abstract
We measured the soluble cytokine CD27 in a variety of thyroid disorders, So luble CD27 was increased in untreated Graves' hyperthyroidism and in euthyr oid ophthalmopathy, Levels of sCD27 were normal after the establishment of euthyroidism with propylthiouracil (PTU) or radio iodine in primary hypothy roidism, chronic thyroiditis, and the hyperthyroid and euthyroid phases of subacute thyroiditis, Soluble CD27 is a marker for cellular activation as i n Graves' hyperthyroidism, but it is not predictive of the outcome of PTU t herapy.