Bicyclization of enynes using the Cp2TiCl2-Mg-BTC system: A practical method to bicyclic cyclopentenones

Authors
Zhao, ZB Ding, Y Zhao, G
Citation
Zb. Zhao et al., Bicyclization of enynes using the Cp2TiCl2-Mg-BTC system: A practical method to bicyclic cyclopentenones, J ORG CHEM, 63(25), 1998, pp. 9285-9291
Citations number
69
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
00223263 → ACNP
Volume
63
Issue
25
Year of publication
1998
Pages
9285 - 9291
Database
ISI
SICI code
0022-3263(199812)63:25<9285:BOEUTC>2.0.ZU;2-E
Abstract
Bicyclic titanacycles 2 generated with the Cp2TiCl2-Mg-P(OEt)(3) system can be trapped with bis(trichloromethyl) carbonate (BTC) to give bicyclic cycl opentenones 3 in good yields. The titanacycle 2m was isolated and well-iden tified. Bicyclization of enynes containing 1,2-disubstituted olefin by this method gave good results with excellent stereoselectivity.