Solitary plasmocytoma of bone in an adolescent

Purpose: To describe an adolescent with solitary plasmocytoma of bone and c ompare the pathologic and radiographic findings with osteomyelitis. Patient and Methods: A 17-year-old girl had a 3-year history of swelling of the right tibia, local pain, and hyperemia. Results: initial biopsy was interpreted as osteomyelitis. The lesion was re biopsied 3 years later and showed a plasma cell neoplasm. A review of the f irst biopsy confirmed a similar histologic picture. Conclusion: Although solitary plasmocytoma of bone is a ran neoplasm in ado lescence, it must be considered in the differential diagnosis of chronic os teomyelitis.