Objective: Document the safety of paranasal sinus surgery in cystic fibrosi
s patients and review the changing trends in paranasal sinus surgery in the
cystic fibrosis population. Study Design: Retrospective review. Materials
and Methods: Chart review of cystic fibrosis patients who underwent paranas
al sinus surgery from 1955 to 1997, Results: Indications for surgery includ
ed chronic sinusitis, nasal obstruction, purulent rhinorrhea, head pain, an
d pyocele, Average duration of anesthesia was 2.1 hours. The complication r
ate from general anesthesia was zero. Excessive bleeding and significant hy
poxia did not occur. Conclusions: Paranasal sinus surgery and general anest
hesia can be safely performed in cystic fibrosis patients. The indications
for paranasal sinus surgery are changing from symptomatic nasal obstruction
to pre-lung transplantation care, Today, treatment has evolved to include
placement of sinus catheters for direct topical instillation of antibiotics
and consideration of maxillary and frontal sinus obliteration.