ENDOGENOUS CODEINE AND MORPHINE IN ANOREXIA AND BULIMIA-NERVOSA

Authors
MARRAZZI MA LUBY ED KINZIE J MUNJAL ID SPECTOR S
Citation
Ma. Marrazzi et al., ENDOGENOUS CODEINE AND MORPHINE IN ANOREXIA AND BULIMIA-NERVOSA, Life sciences, 60(20), 1997, pp. 1741-1747
Citations number
17
Categorie Soggetti
Biology,"Medicine, Research & Experimental","Pharmacology & Pharmacy
Journal title
Life sciences → ACNP
ISSN journal
00243205
Volume
60
Issue
20
Year of publication
1997
Pages
1741 - 1747
Database
ISI
SICI code
0024-3205(1997)60:20<1741:ECAMIA>2.0.ZU;2-H
Abstract
The endogenous plasma alkaloids codeine and morphine were shown to be elevated in patients with anorexia nervosa and bulimia nervosa compare d to control subjects. The role of these opioids in the pathophysiolog y of these eating disorders is discussed in relation to an auto-addict ion opioid model. This model proposes that endogenous opioids are rele ased during an initial period of dieting and reinforce a state of star vation dependence [1,2].