Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures

Authors
Mirza, WU Rak, IW Thadani, VM Cereghino, JJ Garnett, WR Brown, LM Zhang, Y Belendiuk, CW
Citation
Wu. Mirza et al., Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures, NEUROLOGY, 51(6), 1998, pp. 1727-1729
Citations number
8
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROLOGY
ISSN journal
00283878 → ACNP
Volume
51
Issue
6
Year of publication
1998
Pages
1727 - 1729
Database
ISI
SICI code
0028-3878(199812)51:6<1727:SEOC(C>2.0.ZU;2-L
Abstract
We evaluated the use of a new, controlled-release capsule form of carbamaze pine, Carbatrol capsules, in an open-label, multicenter study of 124 patien ts with complex partial seizures. Ninety-one percent of the patients succes sfully completed the 6-month trial with good seizure control, with a signif icant improvement in quality of Life. We conclude that switching patients w ith complex partial seizures from multiple daily-dose carbamazepine to twic e-daily Carbatrol on a milligram-to-milligram basis is relatively safe.